Detection of critical cancer gene mutations in clinical tumor specimens may predict patient outcomes and inform treatment options; however, high-throughput mutation profiling remains underdeveloped as a diagnostic approach.We report the implementation of a genotyping and validation algorithm that enables robust tumor mutation profiling in the clini
The article distinguishes between different forms of normative social critique: an external, an internal or immanent, and a disclosing form of critique.Whereas the external and internal critique neflintw-r6mpw appeal to or rely upon a certain standard or yardstick of critique, the disclosing form of critique aims at here opening up our eyes to new
Conflicts that arise in romantic relationships can be one of the greatest causes of suffering when they are not faced appropriately.Through two studies, this research analyses the differential effect of gender and the influence of emotional intelligence on conflict-facing responses, as well as their consequences at an individual and relationship le
Chromophobe renal cell carcinoma (chRCC) is a distinctive type of malignant kidney tumor characterized by large cells with defined cell membrane.Primary simply southern cat shirt renal neuroendocrine tumors (NET) are rare with morphology similar to NET at other sites.There are few case reports describing the coexistence of these 2 neoplasms within
Innovation is a well-studied cognitive phenomenon related to general intelligence and brain size.Innovative ability varies considerably here within species and it is widely assumed that this variation must have important fitness consequences.However, direct evidence for a link between innovative ability and fitness has rarely been shown.Previous re